Systematic Synthesis and Biological Evaluation of α- and β-D-Lyxofuranosyl Nucleosides of the Five Naturally Occurring Nucleic Acid Bases

DOI: 10.1021/jm00389a005

Source and publish data:

Journal of Medicinal Chemistry p. 982 - 991 (1987)

Update date:2022-09-26

Topics:

Authors:

Gosselin, Gilles

Bergogne, Marie-Christine

Rudder, Jean De

Clercq, Erik De

Imbach, Jean-Louis

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Article abstract of DOI:10.1021/jm00389a005

The α- and β-D-lyxofuranosyl analogues of the naturally occurring nucleosides have been synthesized and their antiviral properties examined.The α anomers were prepared by glycosylation of purine and pyrimidine aglycons with tetra-O-acetyl-α-D-lyxofuranose

Full text of DOI:10.1021/jm00389a005

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