STEREOCONTROLLED FUNCTIONALIZATION OF CYCLOHEPTADIENE; AN APPROACH TO TYLOSIN AND CARBOMYCIN B FROM A COMMON INTERMEDIATE

DOI: 10.1016/S0040-4039(00)84728-0

Source and publish data:

Tetrahedron Letters p. 3111 - 3114 (1986)

Update date:2022-07-29

Topics:

Authors:

Pearson, Anthony J.

Ray, Tapan

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Article abstract of DOI:10.1016/S0040-4039(00)84728-0

Bromolactonization of the cycloheptadienylacetic acid 1 proceeds with good regio- and stereocontrol and provides 4 which serves as a common intermediate for right hand sections of two macrolide antibiotics, tylosin and carbomycin B.

Full text of DOI:10.1016/S0040-4039(00)84728-0

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