
Tetrahedron Letters p. 3595 - 3598 (1986)
Update date:2022-08-04
Topics:
Luessmann, Joerg
Hoppe, Dieter
Jones, Peter G.
Fittschen, Christa
Sheldrick, George M.
The acid-catalyzed ring opening of the title epoxide 1 takes place at the C-1 atom with retention of configuration at C-2 to form 2,3-cis-2-hydroxy-substituted γ-lactol derivatives 3.In basic media, nucleophiles attack the C-2 atom with inversion of confi
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Doi:10.1021/jm8006917
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(1986)