Tetrahedron Letters p. 4095 - 4098 (1986)
Update date:2022-07-31
Topics:
Lipshutz, Bruce H.
Vaccaro, Wayne
Huff, Bret
Monocyclic 4(5)-substituted imidazoles react with SEM-Cl to afford the corresponding N-SEM derivatives.These aminals readily metalate at C-2 with n-BuLi in THF at -78 deg C and react with various electrophiles.Deprotection may be achieved with either n-Bu
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