Substituted Benzamides with Conformationally Restricted Side Chains. 5. Azabicyclo Derivatives as 5-HT4 Receptor Agonists and Gastric Motility Stimulants

DOI: 10.1021/jm00058a004

Source and publish data:

Journal of Medicinal Chemistry p. 683 - 689 (1993)

Update date:2022-07-31

Topics:

Authors:

King, Frank D.

Hadley, Michael S.

Joiner, Karen T.

Martin, Roger T.

Sanger, Gareth J.

et al. et al.

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Article abstract of DOI:10.1021/jm00058a004

The syntheses of benzamides containing azabicyclo side chains and their 5-HT₄ receptor agonist and 5-HT₃ receptor antagonist properties are described.These compounds were designed to mimic higher energy conformations of quinol

Full text of DOI:10.1021/jm00058a004

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