Substituted Benzamides with Conformationally Restricted Side Chains. 5. Azabicyclo Derivatives as 5-HT4 Receptor Agonists and Gastric Motility Stimulants

Article abstract of DOI:10.1021/jm00058a004

The syntheses of benzamides containing azabicyclo side chains and their 5-HT₄ receptor agonist and 5-HT₃ receptor antagonist properties are described.These compounds were designed to mimic higher energy conformations of quinol