Tetrahedron Letters p. 3345 - 3348 (1986)
Update date:2022-07-29
Topics: Total synthesis Reaction Conditions Purification techniques
Burke, Steven D.
Pacofsky, Gregory J.
Piscopio, Anthony D.
The antifungal mold metabolites isoavenaciolide (1b) and avenaciolide (1c) have been synthesized in racemic form a common precursor, α-methylene lactone 4, obtained via a glycolate ester enolate Claisen rearrangement.
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(1921)
