Pharmacokineticts of Catechol Cephalosporins. The Effect of Incorporating Substituents into the Catechol Moiety on Pharmacokinetics in a Marmoset Model

DOI: 10.1021/jm00092a015

Source and publish data:

Journal of Medicinal Chemistry p. 2643 - 2651 (1992)

Update date:2022-09-26

Topics:

Authors:

Bird, T. G. C.

Arnould, J. C.

Bertrandie, A.

Jung, F. H.

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Article abstract of DOI:10.1021/jm00092a015

Two series of cephalosporins A and B have been synthesized, bearing at C-3' catechols substituted with various electron withdrawing groups (Y) and differing links (X), and were evaluated for their in vitro antibacterial activity and their pharmacokinetics

Full text of DOI:10.1021/jm00092a015

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