Journal of Medicinal Chemistry p. 1193 - 1199 (1987)
Update date:2022-07-29
Topics:
Chen, Eugene H.
Tanabe, Keiichi
Saggiomo, Andrew J.
Nodiff, Edward A.
Thirty-two 5-alkoxyprimaquines have been synthesized and evaluated as blood schizonticides (Plasmodium berghei, mouse) and tissue schizonticides (Plasmodium cynomolgi, monkey). Several of these compounds were extremely active in both screens. Such a broad spectrum of antimalarial efficacy offers the possibility of a single drug that could cure the various relapsing and nonrelapsing malarias.
View MoreYingYing Pharmaceutical Co.,Ltd
Contact:86-18854126208
Address:55#, yingxiongshan road
Chemsigma International Co.,Ltd.
website:http://www.chemsigma.com
Contact:86-025-58748998
Address:Rm.705, 15th Building,Rd.Xinke II
website:http://www.tbbmed.com
Contact:86--21-50498136
Address:Room 6002, Building 7-1, No.160 Basheng Road,Pudong Area,Shanghai China
PharmaResources(Kaiyuan)CO,.Ltd
Contact:+86-21-50720028
Address:No.3, Beihuan Road, Economic Development District, Kaiyuan City, Tieling City, Liaoning Province, China 112300
Changsha Goomoo Chemical Technology Co.Ltd
Contact:+86-731-82197655
Address:No.649,Chezhan Rd.(N),Changsha,Hunan,China
Doi:10.1021/ja003507i
(2001)Doi:10.1016/j.bmcl.2009.10.093
(2010)Doi:10.1155/2001/657605
(1921)Doi:10.1021/jo801915c
(2008)Doi:10.1515/HC.2007.13.6.347
(2007)Doi:10.1021/om8007597
(2008)
