Journal of Fluorine Chemistry p. 477 - 484 (1984)
Update date:2022-08-03
Topics:
Jewett, D. M.
Potocki, J. F.
Ehrenkaufer, R. E.
The useful electrophilic fluorinating agent, acetyl hypofluorite, was obtained by passing F2 diluted in N2 through columns containing complexes of alkali metal acetates with acetic acid.Acetyl hypofluorite obtained from KOAc(HOAc)1.5 and o.14percent F2 in N2 was reacted with tri-O-acetyl-D-glucal in CCl3F to obtain tetra-O-acetyl-2-deoxy-2-fluoro-D-glucose in 68percent yield based on F2.These conditions are appropriate to the radiosynthesis of 18F-labeled 2-deoxy-2-fluoro-D-glucose for positron emission tomography.Important variables were the metal cation used, the ratio of HOAc to MOAc and the water content of the complex.
View MoreChangzhou Hopschain Chemical Co.,Ltd
website:http://www.hopschem.cn/products.html
Contact:86-519-85528066
Address:Room 710, Unit A, Xingbei Development Mansion, Tongjiang Road, Changzhou City,213000, China
Contact:86-516-66656369
Address:The west road of Huaihai, Xuzhou, China
Contact:86 21 3772 9386
Address:Rm.1803,Starry Bldg.1,1505 Meijiabang Road,Shanghai 201620 China
ChangZhou XiaQing Chemical Co., Ltd.
Contact:+86-519-88721665
Address:3# Hengluo Road, Henglin Town, Changzhou City, Jiangsu Province，China
Yurui(Shanghai)Chemical Co.,Ltd
Contact:0086 21-50456736
Address:No.3188 Xiupu Road,Shanghai
Doi:10.1055/s-2007-965881
(2007)Doi:10.1021/ja8071463
(2008)Doi:10.1016/j.tet.2008.09.002
(2008)Doi:10.1021/ol802401a
(2008)Doi:10.1016/j.ejmech.2018.03.003
(2018)Doi:10.1021/ja01195a047
(1947)
