Aldosterone Antagonists. 2. Synthesis and Biological Activities of 11,12-Dehydropregnane Derivatives

DOI: 10.1021/jm00392a022

Source and publish data:

Journal of Medicinal Chemistry p. 1647 - 1658 (1987)

Update date:2022-08-02

Topics:

Authors:

Kamata, Susumu

Matsui, Takeaki

Haga, Nobuhiro

Nakamura, Masuhisa

Odaguchi, Kunihiro

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00392a022

Several steroid derivatives having the Δ¹¹-pregnane skeleton with a 17-γ-spirolactone function were synthesized to evaluate their antialdosterone activity and to elucidate the relation between their binding affinity to mineralocorticoid recepto

Full text of DOI:10.1021/jm00392a022

Products guided by the article

Product name:3-<3β-acetoxy-5β,17β-dihydroxy-15β,16β-methylene-6α-(phenylseleno)androst-11-en-17α-yl>propionic acid γ-lactone

Cas No:109050-86-4

R&D Labs maybe for 109050-86-4

zhangjiagang bonded areas banggao co;ltd

website:http://www.shunchangchem.com

Contact:0086-13921972933

Address:Dongsha Chemical Zone.Zhangjiagang, Jiangsu Province
China Synchem Technology Co.,Ltd

website:http://www.cnsynchem.com

Contact:+86-0552-4929311

Address:No.217 Daqing Road
Synasia Inc

Contact:17316303296

Address:240 Amboy Ave
Taizhou Huading Chemical Co.,Ltd(expird)

Contact:+86-576-88583898

Address:Economic&Technology development zone,Taizhou City,Zhejiang Province,China
Xinji City Taida Sinopec Co., Ltd.

Contact:0086-311-85341278

Address:No.6, Nanhua Road,Xinji City Road,Hebei Province,China

Relevant to this article

Efficient access to 2,5-substituted tetrahydrofurans via a one-pot cyclization of di- and triepoxides

Doi:10.1016/j.tetlet.2008.09.053
(2008)
Concise synthesis and crystal structure of [12]cycloparaphenylene

Doi:10.1002/anie.201007232
(2011)
Multimetallic arrays: Symmetrical and unsymmetrical bi-, tri-, and tetrametallic organometallic complexes of ruthenium(II) and osmium(II)

Doi:10.1021/om800686f
(2009)
An expedient synthesis of 3-substituted indoles via reductive alkylation with ketones

Doi:10.1016/j.tetlet.2008.08.034
(2008)
Synthesis of novel purpurealidin analogs and evaluation of their effect on the cancer-relevant potassium channel K_V10.1

Doi:10.1371/journal.pone.0188811
(2017)
Synthesis of dinitrosyl iron complexes (DNICs) with intramolecular hydrogen bonding

Doi:10.1016/j.jorganchem.2008.08.034
(2008)

Article Doi