
Journal of Medicinal Chemistry p. 1647 - 1658 (1987)
Update date:2022-08-02
Topics:
Kamata, Susumu
Matsui, Takeaki
Haga, Nobuhiro
Nakamura, Masuhisa
Odaguchi, Kunihiro
et al.
Several steroid derivatives having the Δ11-pregnane skeleton with a 17-γ-spirolactone function were synthesized to evaluate their antialdosterone activity and to elucidate the relation between their binding affinity to mineralocorticoid recepto
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