Fluoro ketone containing peptides as inhibitors of human renin.

DOI: 10.1021/jm00392a016

Source and publish data:

Journal of medicinal chemistry p. 1617 - 1622 (1987)

Update date:2022-08-03

Topics:

Authors:

Fearon Fearon

Spaltenstein

Hopkins Hopkins

Gelb Gelb

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Article abstract of DOI:10.1021/jm00392a016

The pentapeptide BOC-Phe-Phe-difluorostatone-Leu-Phe-NH2 has been prepared and found to be a potent inhibitor of human renin. This compound contains a difluoromethylene ketone group that exists predominantly in the hydrated form in water. The difluorostat

Full text of DOI:10.1021/jm00392a016

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