
Tetrahedron p. 5403 - 5406 (1986)
Update date:2022-07-29
Topics:
Cock, E. De
Marsenille, M. Van
Auwera, L. Van Der
Tourwe, D.
Binst, G. Van
In order to determine the configuration of the diastereoisomers of the dipeptide analogues L-Pro φ(CH=CH, E) L,D-Phe, a method is described involving reduction of the ethylenic bond and cyclization to the lactams.The 1H NMR spectra of the separated isomers allow the assignment of the S,S or R,S configuration.
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Doi:10.1021/jo802093d
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(1987)