Synthesis of a new class of spirooxindole-benzo[b]thiophene-based molecules as acetylcholinesterase inhibitors

Article abstract of DOI:10.3390/molecules25204671

A series of new oxindole-based spiro-heterocycles bearing the benzo[b]thiophene motif were synthesized via a 1,3-dipolar cycloaddition reaction and their acetylcholinesterase (AChE) inhibitory activity was evaluated. All the synthesized compounds exhibite