
Steroids p. 8 - 11 (1991)
Update date:2022-08-05
Topics:
Curts, Stephen W.
Wren, Douglas L.
Cooper, Gary F.
A convenient synthesis of both 5β, 17α-19-norpregn-20-yne-3β,17-diol (1) and 5β,17α-19-norpregn-20-yne-3α, 17-diol (2) in multigram quantities from estr-4-ene-3, 17-dione is reported. Full characterization of these often-cited human melaholites of norethindrone is presented for the first time.
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Doi:10.1021/ja01473a035
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(2008)