Tetrahedron Letters p. 3787 - 3790 (1986)
Update date:2022-07-29
Topics:
Davies, Stephen G.
Dordor-Hedgecock, Isabelle M.
Sutton, Kevin H.
Walker, Jonathan C.
Michael addition of lithium benzylamide to the enantiomerically pure (S)-E-crotonyl complex of <(η5-C5H5)Fe(CO)(PPh3)> followed by trapping of the resultant enolate with methyl iodide or methanol occurs with high diastereoselectivity and gives after decomplexation the essentially optically pure (3R),(4S)-(-)-3,4-dimethyl- and (4S)-(-)-4-methyl-N-benzyl-β-lactams respectively.Similarly, tandem addition of lithium benzylamide and methylation of the corresponding enantiomerically pure R-(-)-acryloyl complex gave after decomplexation the essentially optically pure (3S)-(-)-3-methyl-N-benzyl-β-lactam.
View Morewebsite:https://www.yurisolar.com/en
Contact:+86-29-81101199
Address:No. 560, East Hangtian Road, Xi'an, China
Zibo Kunran Enterprises Co. LTD
website:http://www.kunranchem.com
Contact:0086 533 5200669
Address:No. 96 Jinjing Avenue, Zibo, Shandong, China
Wuhan Chemchemical Co., Ltd.(expird)
Contact:15973022782
Address:7-5-6218,Incubation Centre,Guandong Industry Park, East Lake High-Tech Development Zone,Wuhan City.
Wuhan Fortuna Chemical Co.,Ltd
website:http://www.fortunachem.com
Contact:86-27-59207850
Address:Add: Room 2015, No.2 Building, Kaixin Mansion No.107 Jinqiao Avenue, Wuhan, China
lianyungang jinkang pharmaceutical technology co., ltd.
Contact:008651885445517
Address:Jinshan industrial park, Ganyu county, Lianyungang, Jiangsu Province, 222115, China
Doi:10.1016/j.jfluchem.2017.09.009
(2017)Doi:10.1134/S1070363207080257
(2007)Doi:10.1039/c2md20298k
(2013)Doi:10.1021/ja00253a022
(1987)Doi:10.1055/s-0028-1083197
(2008)Doi:10.1021/jm010253i
(2001)