Organic Letters
Letter
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AUTHOR INFORMATION
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Corresponding Author
(20) Cu(pyridine)4(OTf)2 proved to be a superior catalyst to
Cu(OTf)2 which was used by Yoshida and co-workers for batch
aziridinations using 1a (ref 14). No attempts were made to recover the
excess alkene from these reactions. Further details of the process
optimization are provided in the Supporting Information.
(21) N-Tosyl derivatives made from 1a were much less effective in
these ring openings. Moreover, extending the residence time for ring
opening with MeOH/H2SO4 to 20 min did not lead to any significant
improvement.
Notes
The authors declare no competing financial interest.
ACKNOWLEDGMENTS
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We thank the University of Warwick for financial support. The
Oxford Diffraction Gemini XRD system was obtained, through
the Science City Advanced Materials project: Creating and
Characterizing Next Generation Advanced Materials. We thank
Dr. Andrew J. Clark (University of Warwick) for the generous
loan of equipment.
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