BIOGENETICALLY-MODELLED TOTAL SYNTHESES (-)-NOCARDICIN A AND (-)-NOCARDICIN G

DOI: 10.1016/S0040-4039(00)83888-5

Source and publish data:

Tetrahedron Letters p. 3819 - 3822 (1986)

Update date:2022-07-31

Topics:

Authors:

Townsend, Craig A.

Salituro, Gino M.

Nguyen, Loan T.

DiNovi, Michael J.

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Article abstract of DOI:10.1016/S0040-4039(00)83888-5

A protected form of L-seryl-D-(p-hydroxyphenyl)glycine was cyclized in a biogenetic sense and partially deprotected to give (-)-t-butyl 3-amino nocardicinate (5) from which (-)-nocardicin A (1) and (-)-nocardicin G (11) were prepared.

Full text of DOI:10.1016/S0040-4039(00)83888-5

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