Journal of the Chemical Society. Chemical communications p. 478 - 480 (1987)
Update date:2022-08-04
Topics:
Haddow, John
Suckling, Colin J.
Wood, Hamish C. S.
2-Amino-7,8-dihydro-6-hydroxymethyl-7-spirocyclopropylpteridin-4(3H)-one is shown to be the first mechanism-based inhibitor of dihydrofolate reductase whereas 2,4-diamino-5-(4-chlorophenyl)-6-cyclopropyl-pyrimidine is a typical competitive inhibitor.
View MoreChangzhou Xuanming Chemical Co., Ltd.
Contact:86 0519 85525329
Address:China Town, Xinbei, Changzhou, Jiangsu Room 6019
Wuhan Hanye Chemical New Material Co.,Ltd
Contact:+86-27-85308141
Address:LiuDian, Panlongcheng Economic Development Zone, HuangPi district, Wuhan, Hubei 430311 P.R.China
Contact:18698110882
Address:1303 No2 building,LuoMa Garden,YongAn Road,Hexi District,Tianjin city
Nantong Kaixin Pharma Chemical Co.,Ltd.
Contact:86-513-85250786
Address:2-1103 Huachen Mansion, 111 Gongnong Road,Nantong, Jiangsu, China
Cerametek Materials（ShenZhen）Co., Ltd.
Contact:+86-755-2324.2554
Address:A3-#9, YongChuan Street, Suite 501
Doi:10.1002/asia.200800483
(2009)Doi:10.1039/b409526j
(2004)Doi:10.1021/acs.orglett.6b00414
(2016)Doi:10.3987/COM-08-S(N)106
(2008)Doi:10.1016/j.tet.2008.10.078
(2009)Doi:10.1016/0223-5234(87)90053-5
(1987)
