Journal of the Chemical Society. Chemical communications p. 478 - 480 (1987)
Update date:2022-08-04
Topics:
Haddow, John
Suckling, Colin J.
Wood, Hamish C. S.
2-Amino-7,8-dihydro-6-hydroxymethyl-7-spirocyclopropylpteridin-4(3H)-one is shown to be the first mechanism-based inhibitor of dihydrofolate reductase whereas 2,4-diamino-5-(4-chlorophenyl)-6-cyclopropyl-pyrimidine is a typical competitive inhibitor.
View Morewebsite:http://www.hope-chem.com
Contact:86-21-58090396-805
Address:Floor 4, Building 5, No.588 Tianxiong Road, Zhoupu International Medical Zone, ShangHai, China
Jiangxi Hito Chemical Co., Ltd.
Contact:+86-792-3170318
Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China
Changyi Xinxing Technology Development Co., Ltd.
Contact:0086-510-86651065(Time Zone:8),86651656
Address:94 Yingbinxilu WestRoad, Huangtu Town, Jiangyin City, Jiangsu, China
NIGNXIA XINDACHANG TECHNOLOGY CO.,LTD
Contact:86-0951-7815345
Address:North side of Qiyuan Road, west side of Yuanfeng Highway, New Material Park, Ningdong Energy and Chemical Industry Base, Ningxia,China
Zhuhai Rundu Pharmaceutical co.,Ltd
Contact:+86-756-7630755
Address:No.6,North Airport Road,Sanzao Town,Jinwan District
Doi:10.1002/asia.200800483
(2009)Doi:10.1039/b409526j
(2004)Doi:10.1021/acs.orglett.6b00414
(2016)Doi:10.3987/COM-08-S(N)106
(2008)Doi:10.1016/j.tet.2008.10.078
(2009)Doi:10.1016/0223-5234(87)90053-5
(1987)
