Synthesis p. 1034 - 1040 (1997)
Update date:2022-07-30
Topics: Amides Nitriles Trifluoroacetic acid Ureas
Shokova, Elvira
Mousoulou, Tasoulla
Luzikov, Yurij
Kovalev, Vladimir
A new preparative method for N-adamantylation of carboxylic acid amides, ureas and for C5-adamantylation of barbituric acid in trifluoroacetic acid (TFA) is proposed. Tertiary 1-adamantanols and 1-(1-adamantyl)alkanols were used as adamantylating agents. The reaction of 1-(1-adamantyl)alkanols with nitriles in TFA solution was employed for the first time for the preparation of N-[1-(1-adamantyl)alkyl]amides.
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Doi:10.1055/s-1994-25628
(1994)Doi:10.1002/adsc.200700331
(2008)Doi:10.1016/j.tet.2008.11.035
(2009)Doi:10.1002/hc.20424
(2008)Doi:10.1055/s-1987-27950
(1987)Doi:10.1039/c3ob27404g
(2013)
