Heterocyclic Quinones with Potential Antitumor Activity. 2. Synthesis and Antitumor Activity of Some Benzimidazole-4,7-dione Derivatives

Article abstract of DOI:10.1021/jm00396a041

A series of benzimidazole-4,7-dione derivatives, bearing substituents at position 1, 2, 5, and 6 of the benzimidazole ring, has been synthesized and tested for antitumor activity in vivo on P388 leukemia.Some of the synthesized compounds show significant