Preparation of Optically Active Cyclic Ether Derivatives of Amino Acids and Peptides

DOI: 10.1039/c39870000474

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 474 - 475 (1987)

Update date:2022-08-04

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Authors:

Barlos, Kleomenis

Papaioannou, Dionysios

Patrianakou, Stella

Sanida, Chariklia

Tsegenidis, Theodoros

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Article abstract of DOI:10.1039/c39870000474

Treatment of N-tritylmethioninol (1) or peptides (6), incorporating methionyl and amino alcohol residues, with MeI, followed by base mediated cyclisation of the thus derived sulphonium salts, provides the title compounds in excellent yields.

Full text of DOI:10.1039/c39870000474

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