Convenient amination of weakly activated thiophenes, furans and selenophenes in aqueous media

Article abstract of DOI:10.1016/S0040-4020(99)00318-X

We describe herein a new amination procedure of weakly activated heterocyclic bromo derivatives in aqueous media. The base catalysed mechanism of this reaction is also confirmed. Moreover, the application of this strategy to the preparation of amino furans and selenophenes is outlined.