Chemistry of Heterocyclic Compounds p. 74 - 77 (1987)
Update date:2022-07-29
Topics:
Zhuk, R. A.
Ludzisha, A. S.
Kostyanovskii, R. G.
Reactions were studied of 5-fluorouracil and thymine with formaldehyde and secondary amines (piperidine, morpholine) and also of their 2,4-bis(trimethylsilyl) derivatives with N-methoxymethylmorpholine and bis(amino)methanes.The N-aminomethylation products are slightly stable and in aqueous solutions decompose readily to the starting components; their structure was confirmed by PMR spectra.
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