Efficient and flexible access to fully protected trinucleotides suitable for DNA synthesis by automated phosphoramidite chemistry

DOI: 10.1039/cc9960002677

Source and publish data:

Chemical Communications p. 2677 - 2678 (1996)

Update date:2022-07-29

Topics:

Authors:

Zehl, Andrea

Starke, Antje

Cech, Dieter

Hartsch, Thomas

Merkl, Rainer

Fritz, Hans-Joachim

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Article abstract of DOI:10.1039/cc9960002677

An efficient synthetic approach to protected trinucleotide phosphoramidites suitable for codon-by-codon synthesis of structural gene combinatorial libraries is described; the procedure rests on the use of a pair of orthogonal protecting groups for the two

Full text of DOI:10.1039/cc9960002677

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