A Short, Efficient, Stereoselective Synthesis of Functionalized Cyclopropanes through the Cyclization of N-Phenyl-3-phenylthio-2-(phenylthiomethyl)propanamide

Article abstract of DOI:10.1246/cl.1987.809

Treatment of N-phenyl-3-phenylthio-2-(phenylthiomethyl)propanamide with 3.3 equiv. of butyllithium in THF-TMEDA produced a new dianion of 2-(phenylthio)cyclopropanecarboxamide which could react with a variety of electrophiles to give cyclopropanes with hi