REACTIONS WITH CHLOROSULFONYL/CHLOROCARBONYL ISOCYANATES: SYNTHESIS OF PYRROLO-1,2,4-BENZOTHIADIAZIN-3(2H)-ONE 1,1-DIOXIDES AND 1H-PYRROLOQUINAZOLINE-1,3(2H)-DIONES

Article abstract of DOI:10.3987/R-1986-12-3397

6-Substituted 2,3-diphenylindoles on reaction with chlorosulfonyl/chlorocarbonyl isocyanates, followed by cyclization with aluminium chloride afforded 9-substituted 5,6-diphenylpyrrolo<1,2,3-de>-1,2,4-benzothiadiazin-3(2H)-one, 1,1-dioxides 2 and 9-substituted 5,6-diphenyl-1H-pyrrolo<3,2,1-ij>-quinazoline-1,3(2H)-diones 3 respectively.In these reactions, an electron donating substituent such as methyl group at position 6 in indole is necessary for cyclization.