Quinazoline Carboxylic Acids, Part X. Synthesis of 1-Methyl-2,4-dioxo-quinazolin-3-yl-acetic Acid, 2,4-Dioxo-quinazolin-1-yl-acetic Acids, 2,4-Dioxo-1,3-quinazolinediacetic Acids and Their Esters

Article abstract of DOI:10.1007/BF00810042

2,4-Dioxo-quinazolin-1-yl-acetic acid esters (2) were prepared by the reaction of either 3,1-benzoxazine-2,4-diones (1) with urea in the melt or in solution or of the substituted anthranilic acid ester 4 with potassium cyanate in acid solution.The anthran