Tetrahedron Letters p. 1665 - 1668 (1987)
Update date:2022-07-29
Topics:
Jouin, P.
Castro, B.
Zeggaf, C.
Pantaloni, A.
Senet, J.P
et al
Mono-esters of N-protected di-acids aspartic and glutamic are prepared by a one-pot activation with alkyl chloroformates or isopropenyl chloroformate and an additionnal alcohol.This process involves the intermediate internal anhydride formation.
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