Synthesis of a novel cyclic sulfone dihydropyridine: An investigation of the isomerization reaction converting an exocyclic double bond isomer into a 1,4-dihydropyridine

DOI: 10.1002/jhet.5570310216

Source and publish data:

Journal of Heterocyclic Chemistry p. 351 - 355 (1994)

Update date:2022-08-04

Topics:

Authors:

Fenk Fenk

Conley Conley

Lindabery

Stefanick

Royster Royster

Dodd Dodd

Schwender

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Article abstract of DOI:10.1002/jhet.5570310216

An eight membered cyclic sulfone 1,4-dihydropyridine, RWJ 22726, 1, with remarkable cardiovascular activity was prepared by isomerization of an exocyclic double bond isomer using various reaction conditions. Under acidic and thermal isomerization conditio

Full text of DOI:10.1002/jhet.5570310216

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