Organic and Biomolecular Chemistry p. 589 - 597 (2009)
Update date:2022-08-04
Topics:
Miller, Marc
Vogel, Johannes C.
Tsang, William
Merrit, Andrew
Procter, David J.
The reaction of thiols with glyoxamides provides a convenient method for the generation of thionium ions and the initiation of Pummerer-type reactions. When the glyoxamides contain tethered aromatic nucleophiles, N-heterocycles are formed by a thionium ion cyclisation. The scope and mechanism of the connective Pummerer-type process has been investigated using a range of thiols, Lewis acids and both mono- and bis-glyoxamides. The utility of the process has been illustrated in a synthesis of the indoloquinoline natural product, neocryptolepine. The Royal Society of Chemistry 2009.
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Doi:10.1016/j.tet.2008.12.057
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