Direct Chain Elongation of N-Carbamoylpyroglutamate. An Efficient Synthesis of (-)-Pyrrolidine-2,5-Dicarboxylic Acid

DOI: 10.1246/cl.1987.2091

Source and publish data:

Chemistry Letters p. 2091 - 2094 (1987)

Update date:2022-08-02

Topics:

Authors:

Ohta, Tomihisa

Hosoi, Akio

Kimura, Toshihiko

Nozoe, Shigeo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1987.2091

(-)-Pyrrolidine-2,5-dicarboxylic acid, an acidic amino acid component of marine red Schizymenia dubyi, has been synthesized with a direct chain elongation reaction of N-carbamoylpyroglutamates at C-5 and a pyrrolidine ring formation.

Full text of DOI:10.1246/cl.1987.2091

Products guided by the article

Product name:(2S,5S)-Pyrrolidine-1,2,5-tricarboxylic acid 1-benzyl ester 2-tert-butyl ester

Cas No:113400-41-2

R&D Labs maybe for 113400-41-2

Yangzhou Zhongbao Pharmaceutical Co.,Ltd

Contact:+86-514-88290838

Address:Jiangsu Baoying county economic develpment zone in baoying avenue91
Nantong LiKai Chemical Co.,Ltd

Contact:+86-513-89068669

Address:Jincheng Science Park
Dalian Synco Chemical Co., Ltd.

Contact:+86-411-83635150

Address:Rm 1004, 24, Tangshan Street, Dalian
Weifang Yukai Chemical Co.,Ltd.

website:http://www.yukaichem.com/en.html

Contact:+86-536-8865336

Address:binhai economic development zone，262737 shangdong，china
Chemsigma International Co.,Ltd.

website:http://www.chemsigma.com

Contact:86-025-58748998

Address:Rm.705, 15th Building,Rd.Xinke II

Relevant to this article

Syntheses and structures of tris-β-diketiminate lanthanide complexes and their high activity for ring-opening polymerization of ε-caprolactone and L-lactide

Doi:10.1002/ejic.200900313
(2009)
Re₂O₇ catalyzed dienone-phenol rearrangement

Doi:10.1039/c5ra04931h
(2015)
Enantiospecific Solvolytic Functionalization of Bromochlorides

Doi:10.1021/jacs.7b07792
(2017)
Rodent selectivity of piperidine-4-yl-1H-indoles, a series of CC chemokine receptor-3 (CCR3) antagonists: Insights from a receptor model

Doi:10.1016/j.bmcl.2014.11.063
(2015)
Short-acting T-type calcium channel antagonists significantly modify sleep architecture in rodents

Doi:10.1021/ml100170e
(2010)
Dipicolinate as acceptor in D-π-A chromophores: synthesis, characterization and fluorescence following single- and two-photon excitation

Doi:10.1016/j.tetlet.2008.09.073
(2008)

Article Doi