Chemistry of Heterocyclic Compounds p. 395 - 399 (1987)
Update date:2022-09-26
Topics:
Blokhina, A. V.
Boronin, V. G.
Druzhinina, V. V.
Zhestkov, V. P.
Portnov, Yu. N.
Intramolecular alkylation of the arylhydrazides of γ-chlorobutyric acid in the presence of sodium ethoxide leads to the formation of N-arylamino-2-pyrrolidones.The direction of the reaction is not altered by the absence of a substituent on the aniline nitrogen atom.In the case of a p-nitrophenyl-hydrazide, O-alkylation is observed.
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