Convenient Synthesis of 4-Nitrotetralones by Selective Side-chain Nitration of Methyl-substituted Acryloylbenzenes, followed by Intramolecular Michael Reaction

DOI: 10.1039/c39870001091

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Journal of the Chemical Society. Chemical communications p. 1091 - 1092 (1987)

Update date:2022-08-05

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Authors:

Keumi, Takashi

Inagaki, Toshihiko

Nakayama, Norihiro

Morita, Toshio

Kitajima, Hidehiko

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Article abstract of DOI:10.1039/c39870001091

Reaction of polymethyl-substituted acryloylbenzenes (1) with fuming nitric acid in acetic anhydride gave the products (2) derived from selective side-chain nitration at the ortho-position; the subsequent intramolecular michael reaction leads to exclusive

Full text of DOI:10.1039/c39870001091

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