Methods for Indole Alkaloid Synthesis: A Study of the Compatibility of the Indole-2,3-Quinodimethane Strategy for the Synthesis of 16-Methoxy-Substituted Aspidosperma-Type Alkaloids. Synthesis of (+)- and (-)-16-Methoxytabersonine

DOI: 10.1021/ja00215a039

Source and publish data:

Journal of the American Chemical Society p. 2242 - 2248 (1988)

Update date:2022-07-29

Topics:

Authors:

Cardwell, Kevin

Hewitt, Brian

Ladlow, Mark

Magnus, Philip

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00215a039

4-Methoxy-2-nitroaniline (5) is converted into 1-carbomethoxy-6-methoxy-3-formyl-2-methylindole (10) in an overall yield of 28percent through five steps.The derived imine from 10 and 2-(phenylthio)ethylamine on treatment with acid chloride (+/-)-12 gave h

Full text of DOI:10.1021/ja00215a039

Products guided by the article

Product name:(1S,2R,3S,4R)-3-Propionyl-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; compound with (1R,2S)-2-methylamino-1-phenyl-propan-1-ol

Cas No:113471-34-4

R&D Labs maybe for 113471-34-4

Hefei Highzone Fine Chemical S&T CO.,LTD

Contact:86-0551-63663560

Address:room 1801 NO. 24 Shuguang RD.
Jiangsu Hualun Chemical Industry Co., Ltd

website:http://www.hualunchem.com

Contact:+86-0514-86464168 86507985

Address:39# Middle Renmin Road, Dinghuo Town
Shandong united-rising pharmaceutical cooperation.,ltd.

Contact:008653187965009

Address:171No., Jing5 Road, Shizhong District, Jinan, China
Shifang Taifeng New Flame Retardant Co., Ltd

Contact:02884721008

Address:tingjiang industrial park, hefeng town
ABA Chemicals (Shanghai) Limited

Contact:021- 5115 9199-232

Address:Suite 18D, #201 Ningxia Road,

Relevant to this article

Peracid Oxidation of 4-Isoxazolines as a Method for the Preparation of α, β-Unsaturated Carbonyl Compounds

Doi:10.1021/jo00245a021
(1988)
An efficient synthesis of [¹³C₆]-3,5-dichloroaniline

Doi:10.1002/jlcr.1521
(2008)
Total synthesis of dl-cephalotaxine. The first example of an intramolecular 4 + 2 cycloaddition where the dienophile has been delivered from the face opposite to the tethering moiety

Doi:10.1021/ja00215a076
(1988)
THE CHEMISTRY OF PHOTOLYTICALLY AND THERMALLY GENERATED α-KETOCARBENES FROM IODONIUM YLIDES OF β-DIKETONES

Doi:10.1016/S0040-4039(00)96535-3
(1987)
Nickel-Catalyzed Cross-Coupling of Redox-Active Esters with Boronic Acids

Doi:10.1002/anie.201605463
(2016)
NEW SYNTHESIS OF BENZO<α>QUINOLIZIDIN-2-ONES via PROTECTED 2-ARYL-4-PIPERIDONES

Doi:10.1016/S0040-4020(01)86842-3
(1987)

Article Doi