Synthesis of Optically Pure α-Alkylated α-Amino Acids and a Single-Step Method for Enatiomeric Excess Determination

DOI: 10.1021/jo00243a049

Source and publish data:

Journal of Organic Chemistry p. 1826 - 1827 (1988)

Update date:2022-08-02

Topics:

Authors:

Kruizinga, Wim H.

Bolster, John

Kellogg, Richard M.

Kamphuis, Johan

Boesten, Wilhelmus H. J.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00243a049

A method for the enzymatic resolution of the amides of some racemic α-alkylated amino acids is described as well as a method involving derivatization with (S)-2-chloropropionyl chloride followed by 1H NMR analysis to establish the enantiomeric excesses of the free amino acids.

Full text of DOI:10.1021/jo00243a049

Products guided by the article

Product name:Pentanamide, 2-amino-2,4-dimethyl-, (R)-

Cas No:113565-54-1

R&D Labs maybe for 113565-54-1

Jinan Hongfangde Pharmatech Co.LTD

Contact:0531-88870908

Address:F Bldg,750#,Shunhua Rd,New&High-tech Zone,Jinan,Shandong,China 250101
Hebei Think-Do Environment Co., Ltd

website:http://www.thinkdo-environment.com

Contact:0311-86510809

Address:No 6, Shilian Middle Street, Circular Chemical Industry Park
Neworld Chemical Co., Ltd Shanghai(expird)

Contact:+86-21-62202658

Address:11F, Blvd 2, No. 1969 PuXing Rd, Shanghai
Lanzhou SchiffChem Co.,Ltd

Contact:86-931-8272767

Address:Room 602, No.461, Nanchang Road, Chengguan District, Lanzhou City, China PRC
Nanjing lanbai chemical Co.,Ltd.

Contact:+86-25-85499326

Address:Room 908, 9F Taiyue Building,No.285 Heyan Road

Relevant to this article

Synthesis of S-glycosyl primary sulfonamides

Doi:10.1021/jo9000367
(2009)
Novel zinc porphyrin sensitizers for dye-sensitized solar cells: Synthesis and spectral, electrochemical, and photovoltaic properties

Doi:10.1002/chem.200801572
(2009)
PREPARATION OF 2,3,4,5-TETRAHYDRO-1,2,4,TRIAZINE-3-ONES

Doi:10.1007/BF00475374
(1987)
Does Formal Intramolecular Transfer of an Acidic Deuterium to a Site of Halogen-Lithium Exchange Show That Lithium-Halogen Exchange Is Faster than Loss of the Acidic Deuterium? Evidence in Favor of an Alternative Mechanism

Doi:10.1021/ja00219a031
(1988)
Dehydrogenative amide synthesis from alcohol and amine catalyzed by hydrotalcite-supported gold nanoparticles

Doi:10.1016/j.tetlet.2012.04.048
(2012)
Monoalkyllanthanide complexes with new β-diketiminato derivative dianionic ligand

Doi:10.1021/om900040r
(2009)

Article Doi