Reaction of Ester Enolates with Nucleophiles. Stereocontrolled Formation of Ketone and Aldehyde Enolates

DOI: 10.1021/jo00243a050

Source and publish data:

Journal of Organic Chemistry p. 1828 - 1830 (1988)

Update date:2022-08-03

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Authors:

Fehr, Charles

Galindo, Jose

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Article abstract of DOI:10.1021/jo00243a050

Lithium enolates of carboxylic and thiocarboxylic esters react with nucleophiles to afford ketone and aldehyde enolates and subsequently their enol silyl ethers diastereoselectively.This reaction is applied to the synthesis of γ-damascone, α-damascone, β-safranal, and artemisia ketone.

Full text of DOI:10.1021/jo00243a050

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