Chemical and Pharmaceutical Bulletin p. 2164 - 2166 (1994)
Update date:2022-08-02
Topics:
Atsuumi
Ikeura
Honma
Morishima
A dihydroxyethylene isostere, (2S,3R,4S)-4-amino-5-cyclohexyl-1-morpholino-2,3-pentanediol (ACMP, 1), which is a component of non-peptidic, orally active, low-molecular-weight renin inhibitors, was synthesized stereospecifically starting from 3-cyclohexyl
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Doi:10.1039/jr9580002209
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(1987)Doi:10.3987/COM-08-11529
(2009)Doi:10.1002/adsc.200800359
(2008)Doi:10.1016/j.tet.2008.10.110
(2009)
