Novel synthesis of a dihydroxyethylene isostere of renin inhibitors

DOI: 10.1248/cpb.42.2164

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2164 - 2166 (1994)

Update date:2022-08-02

Topics:

Authors:

Atsuumi Atsuumi

Ikeura Ikeura

Honma Honma

Morishima

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.42.2164

A dihydroxyethylene isostere, (2S,3R,4S)-4-amino-5-cyclohexyl-1-morpholino-2,3-pentanediol (ACMP, 1), which is a component of non-peptidic, orally active, low-molecular-weight renin inhibitors, was synthesized stereospecifically starting from 3-cyclohexyl

Full text of DOI:10.1248/cpb.42.2164

NII-Electronic Library Service

Products guided by the article

Product name:methyl cis-(4S)-(N-benzyloxycarbonyl)amino-5-cyclohexyl-2-pentenate

Cas No:113828-84-5

R&D Labs maybe for 113828-84-5

Shanghai Profirst Co., Ltd.

Contact:+86-21-38122007

Address:2, Lane 1123, Kangqiao Road, Pudong New Area, Shanghai
TIANJIN FESTO CHEMICAL CO.,LTD(expird)

Contact:86-22-25814570

Address:No.12th,5th Ave.,TEDA,Tianjin,China
xujianqiang

Contact:86-21-57725962

Address:shanghai
Changzhou Ruiping Chemical Co., Ltd

website:http://www.wishchem.com

Contact:+86-519-82324280

Address:No.288-1 Huacheng Road, Jintan
Shanghai Yuantai Chemical Products Co., Ltd

Contact:021--66129803

Address:Chengyin Road,Shanghai,China

Relevant to this article

Doi:10.1039/jr9580002209
(1958)
SYNTHESIS AND REARRENGEMENTS OF ortho-SELENONIUM PHENOXIDES

Doi:10.1016/S0040-4039(01)83847-8
(1987)
Doi:10.1016/0008-6215(87)80110-6
(1987)
Synthesis of related substances of cilostazol

Doi:10.3987/COM-08-11529
(2009)
Highly efficient heterogeneous aqueous Kharasch reaction with an amphiphilic resin-supported ruthenium catalyst

Doi:10.1002/adsc.200800359
(2008)
Gold(I)-catalyzed intermolecular hydroarylation of allenes with nucleophilic arenes: scope and limitations

Doi:10.1016/j.tet.2008.10.110
(2009)

Article Doi