
Chemical and Pharmaceutical Bulletin p. 131 - 135 (1992)
Update date:2022-07-29
Topics:
Yaegashi
Nokata
Sawada
Furuta
Yokokura
Miyasaka
Water-soluble derivatives having the lactone ring intact were synthesized starting from 7-ethyl-10-hydroxycamptothecin (1). Glycosides (2) of the phenolic hydroxyl group of 1 were obtained by reaction with acetylated α-bromosugars in acetone or aqueous ac
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