Renal vasodilators. The role of the 4-substituent in isoquinolin-3-ol cardiovascular agents: 4-Ureido derivatives of isoquinolin-3-ol with selective renal vasodilator properties

DOI: 10.1021/jm00125a011

Source and publish data:

Journal of Medicinal Chemistry p. 990 - 997 (1989)

Update date:2022-07-30

Topics:

Authors:

Kanojia Kanojia

Lever Jr.

Press Press

Williams

Werblood

Giardino

Falotico

Tobia Tobia

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Article abstract of DOI:10.1021/jm00125a011

The synthesis and cardiovascular evaluation of a series of isoquinolin-3-ol derivatives bearing a variety of nitrogen substituents (amino, acylamino, carbamate, and ureido) at C-4 are described. Certain of these compounds have a selective renal vasodilati

Full text of DOI:10.1021/jm00125a011

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