Nucleosides of 1,4-thiazin-3-one and derivatives as tetrahedral intermediate analogues of enzymes in pyrimidine nucleoside metabolism

DOI: 10.1021/jm00403a015

Source and publish data:

Journal of Medicinal Chemistry p. 1575 - 1579 (1988)

Update date:2022-07-30

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Authors:

Marcus Marcus

Gundy Gundy

Levenson

Meyer Jr.

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Article abstract of DOI:10.1021/jm00403a015

Reaction of the trimethylsilylated derivative of 1,4-thiazin-3-one with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose in the presence of SnCl₄ gave, after deblocking, 4-β-D-ribofuranosyl-1,4-thiazin-3-one (8). Treatment of 1,4-thiazin-3-one wit

Full text of DOI:10.1021/jm00403a015

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