Nucleosides of 1,4-thiazin-3-one and derivatives as tetrahedral intermediate analogues of enzymes in pyrimidine nucleoside metabolism

Article abstract of DOI:10.1021/jm00403a015

Reaction of the trimethylsilylated derivative of 1,4-thiazin-3-one with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose in the presence of SnCl₄ gave, after deblocking, 4-β-D-ribofuranosyl-1,4-thiazin-3-one (8). Treatment of 1,4-thiazin-3-one wit