STUDIES DIRECTED TOWARD THE TOTAL SYNTHESIS OF THE MILBEMYCINS: SYNTHESIS OF THE C11 TO C31 FRAGMENT OF MILBEMYCIN D

DOI: 10.1016/S0040-4039(00)96346-9

Source and publish data:

Tetrahedron Letters p. 3651 - 3654 (1987)

Update date:2022-07-29

Topics:

Authors:

Crimmins, Michael T.

Hollis, W. Gary

Bankaitis-Davis, Danute M.

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Article abstract of DOI:10.1016/S0040-4039(00)96346-9

A highly stereocontrolled synthesis of the C11 to C31 fragment of the potentantimicrobial agent milbemycin D has been completed.This approach utilizes a unique hydrolysis-cyclization to construct the spiroketal portion of the molecule.

Full text of DOI:10.1016/S0040-4039(00)96346-9

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