Tetrahedron Letters p. 6397 - 6400 (1987)
Update date:2022-07-30
Topics:
Elburg, P. A. van
Honing, G. W. N.
Reinhoudt, D. N.
Chiral four-membered cyclic nitrones were synthesized by the asymmetric (4+2)-cycloaddition of nitroalkenes 1 and chiral ynamines 2.The subsequent stereoselective addition of nucleophiles to these nitrones enabled the synthesis of chiral N-hydroxyazetidines.
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Doi:10.1039/b816768k
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