Journal of Medicinal Chemistry p. 7289 - 7300 (2009)
Update date:2022-08-04
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A series of benzoxazinones was synthesized and evaluated as novel long chain fatty acid elongase 6 (ELOVL6) inhibitors. Exploration of the SAR of the UHTS lead 1a led to the identification of (S)-1y that possesses a unique chiral quarternary center and a
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Doi:10.1002/chem.200800797
(2009)Doi:10.1039/b817599c
(2009)Doi:10.1021/jm801445c
(2009)Doi:10.1016/j.tet.2009.04.086
(2009)Doi:10.1016/j.tetlet.2009.01.112
(2009)Doi:10.1021/jo00247a014
(1988)
