Imidazopyrimidines and Imidazopyrazines: The Role of Nitrogen Position in Inotropic Activity

DOI: 10.1021/jm00403a018

Source and publish data:

Journal of Medicinal Chemistry p. 1590 - 1595 (1988)

Update date:2022-07-29

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Authors:

Spitzer, Wayne A.

Victor, Frantz

Pollock, G. Don

Hayes, J. Scott

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Article abstract of DOI:10.1021/jm00403a018

Congestive heart failure is a major medical problem for which existing medicaments have provided limited benefit.Recent new experimental drugs, including imidazo<4,5-b>- and imidazo<4,5-c>pyridines, have both inotropic and vasodilatory properties.Subtle c

Full text of DOI:10.1021/jm00403a018

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