Synthesis of (aryloxy)alkylamines. 2. Novel imidazo-fused heterocycles with calcium channel blocking and local anesthetic activity

DOI: 10.1021/jm00119a026

Source and publish data:

Journal of Medicinal Chemistry p. 2221 - 2227 (1988)

Update date:2022-09-26

Topics:

Authors:

Sanfilippo

Urbanski

Press Press

Dubinsky

Moore Jr.

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Article abstract of DOI:10.1021/jm00119a026

A series of imidazo-fused heterocycles substituted with an (aryloxy)alkylamine side chain were prepared as modifications to butoprozine (I) and found to possess calcium channel blocking activity similar in potency to that of bepridil in trachea smooth mus

Full text of DOI:10.1021/jm00119a026

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