
Tetrahedron Letters p. 3827 - 3830 (1987)
Update date:2022-08-03
Topics:
Shin, Chung-gi
Obara, Takumi
Segami, Shigenori
Yonezawa, Yasuchika
Two kinds of basic N-carboxy α-dehydroamino acid anhydrides (ΔNCA) were synthesized by the cyclization of N-benzyloxycarbonyl (Cbz)-α-dehydro-ornithine and -lysine (DHA), derived from Cbz-aminoaldehydes and N-Cbz-2-(diethoxyphosphinyl)glycine esters.Moreover, facile conversion of Cbz as Nα-protecting group in DHA to Boc via ΔNCA was also successful.
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