Tetrahedron p. 3371 - 3386 (1987)
Update date:2022-08-02
Topics:
Suginome, Hiroshi
Yamada, Shinji
We describe a new general method for the synthesis of medium-sized lactones based on ring-enlargement via a regioselective β-scission of alkoxyl radicals generated by photolysis from the hypoiodites of several catacondensed lactols.The syntheses of 9-membered lactones from 6/5 fused lactols, 10-menbered lactones including a naturally occuring lactone, phoracantholide I, from 6/6 or 7/5 fused lactols, and 11-membered lactones from 7/6 or 8/5 fused lactols are shown to be achieved by the present method.This new method may have a potential for application to the synthesis of either smaller or larger-sized lactones.
View Morewebsite:http://www.sjc.com.tw
Contact:(886) 2-2396-6223
Address:14Fl., No. 99. Sec. 2, Jen Ai Road
website:http://www.shengmaochem.com
Contact:86-27-82853423, 82819281
Address:Rm 202, A Unit Huaqiao Building No. 2, Lihuangpi Road, Wuhan, China
website:http://www.enbridgepharm.com
Contact:+86-510-83591909
Address:Huishan Zone, Wuxi City, Jiangsu Province, P.R.China
Shanghai Egoal Chemical Co.,Ltd
Contact:+86-21-50333091
Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
website:http://www.shochem.com
Contact:021-50800795
Address:No.1043, Halei Rd, Zhangjiang Hi-Tech Park, Shanghai, Postcode 201203, China
Doi:10.1055/s-0036-1588343
(2016)Doi:10.1016/j.bmcl.2007.03.016
(2007)Doi:10.1021/jo00251a008
(1988)Doi:10.1002/adsc.200606164
(2006)Doi:10.1021/jacs.0c11424
(2021)Doi:10.1021/jo00250a029
(1988)