Journal of Organic Chemistry p. 3568 - 3572 (1988)
Update date:2022-08-02
Topics:
Taylor, Edward C.
Pont, Joseph L.
Warner, John C.
7-Azalumazines tethered at the C6 position with a series of dienophilic side chains undergo intramolecular Diels-Alder reactions to provide 6,7-annulated lumazines and 8-deazalumazines.The rates of these cycloaddition reactions are markedly faster than for previously reported cycloadditions of isomeric C7-tethered 6-azalumazines.On the other hand, 7-azalumazines do not undergo intermolecular Diels-Alder reactions with enamine dienophiles, whereas under identical conditions, 6-azalumazines react readily.Reasons for this striking reversal in reactivity observed for inter- and intramolecular Diels-Alder reactions of 6- vs 7-azalumazines are discussed.
View MoreNanjing Capatue Chemical Co., Ltd
Contact:+86-25-86371192 +86-025-85720158
Address:No.20 Jiangjun Avenue, Jiangning Economic & Technical Development Zone
Zhejiang Linhai Xinhua Chemicals Factory
Contact:0086-13661858911
Address:Xunqiao Development Zone, Linhai, Zhejiang, China
Shanghai Bojing Chemical Co., Ltd.
Contact:021-37122233
Address:6F Buildiing 11,No.388,Baifu Road,District Fengxian.Shanghai, China.
website:http://www.tbbmed.com
Contact:86--21-50498136
Address:Room 6002, Building 7-1, No.160 Basheng Road,Pudong Area,Shanghai China
Anhui Sunsing Chemicals Co.,Ltd
website:http://www.sunsingchem.com
Contact:0086-566-2023179
Address:Jin An industry park, Chizhou economic technical development zone, Anhui
Doi:10.1039/jr9262901578
(1926)Doi:10.1038/nchem.651
(2010)Doi:10.1016/j.bmcl.2009.02.031
(2009)Doi:10.1002/anie.200805680
(2009)Doi:10.1248/cpb.38.3202
(1990)Doi:10.1016/j.bmc.2014.12.036
(2015)
