Tetrahedron Letters p. 5551 - 5554 (1987)
Update date:2022-08-04
Topics:
Costa, Antonio
Saa, Jose M.
The direct metalation of several p-hydroxybenzylmethyl ethers has been studied.Those substrates possesing an electron-withdrawing group in a 1,3 relationship with the coordinating (-CH2OMe) group underwent regioselective metalation by the action of n-BuLi/THF.Highly substituted phenols can thus be readily prepared.
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Doi:10.1016/S0040-4039(00)96655-3
(1987)Doi:10.1007/BF00958359
(1987)Doi:10.1139/v61-088
(1961)Doi:10.1021/ja00867a023
(1962)Doi:10.1016/j.ejmech.2008.10.039
(2009)Doi:10.1002/chem.200901048
(2009)
