AN AZIRIDINE ROUTE TO CHIRAL β-LACTAMS A NOVEL ENTRY TO (+)-THIENAMYCIN

DOI: 10.1016/S0040-4039(00)95328-0

Source and publish data:

Tetrahedron Letters p. 1211 - 1214 (1987)

Update date:2022-09-26

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Authors:

Tanner, David

Somfai, Peter

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Article abstract of DOI:10.1016/S0040-4039(00)95328-0

Enantiomerically pure 2,3-epoxy alcohols are transformed readily and stereospecifically to the corresponding aziridines, regioselective ring-opening of which allows subsequent conversion to chiral β-lactams suitable for elaboration to the title antibiotic

Full text of DOI:10.1016/S0040-4039(00)95328-0

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